KDM5D epigenetically represses FERD3L to inhibit tumor growth in male colorectal cancer

Key Points

• Tumor growth is inhibited by KDM5D through the repression of FERD3L, indicating its role in colorectal cancer.
• The analysis shows a significant relationship between KDM5D levels and tumor progression metrics in males.
• Observational analysis across different male colorectal cancer samples highlights the epigenetic role of KDM5D.
• Findings suggest KDM5D may be a valuable therapeutic target, requiring further exploration in male-specific colorectal cancer.