Inflammation-associated depression in cholangiocarcinoma: impacts of surgical resection and radiotherapy

Key Points

• Depression prevalence is significantly increased in patients with cholangiocarcinoma undergoing treatment.
• In a cohort, patients experienced higher depression scores post-surgical resection and radiotherapy than before.
• Analysis highlights how inflammation correlates with depression severity during treatment.
• Implications indicate that managing inflammation may improve mental health outcomes in cancer therapy.