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Tardigrade Dsup: Interactions with DNA and protection of cells from oxidative stress | Synapse
March 3, 2026
Tardigrade Dsup: Interactions with DNA and protection of cells from oxidative stress
GN
Gavin Shuyang Ni
La Jolla Science Applications (United States)
HS
Hetian Su
University of California, San Diego
YZ
Yanxuan Zhu
University of California, San Diego
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Key Points
Cells exposed to oxidative stress demonstrate enhanced survival when treated with tardigrade Dsup protein, showing promising protective effects.
Survival rates of cells under oxidative conditions improved significantly with Dsup application, as observed in various experimental models.
Analysis of molecular interactions indicates that Dsup directly interacts with DNA, providing insights into its protective mechanisms.
Due to its potential for enhancing cell resilience, Dsup may enable novel applications in biomedical fields.
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Cite This Study
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Ni et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75ec1c6e9836116a29a5e
https://doi.org/https://doi.org/10.1016/j.bpj.2026.01.048