Sitagliptin alleviates cyclophosphamide-induced oxidative stress and testicular toxicity in Wistar rats

Key Points

• Sitagliptin reduces testicular toxicity caused by cyclophosphamide, improving overall testicular health.
• The treatment significantly lowers markers of oxidative stress, providing protective effects on the testes.
• Analysis in Wistar rats demonstrates that antioxidants may play a key role in mitigating drug side effects.
• Findings suggest that sitagliptin could lead to safer treatment options for conditions requiring cyclophosphamide.