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Palmitoylated STX11 suppresses AMPK to drive lipogenesis and colorectal cancer | Synapse
March 3, 2026
Palmitoylated STX11 suppresses AMPK to drive lipogenesis and colorectal cancer
BL
Bao Yong li
ZY
Zhongkang Yan
WD
Wenyuan Dang
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Key Points
Palmitoylated STX11 drives lipogenesis in colorectal cancer cells, enhancing tumor growth.
The study shows a significant decrease in AMPK activity associated with high levels of STX11.
Using biochemical assays, researchers analyzed the impact of STX11 on metabolic pathways in cancer cells.
These findings may suggest potential therapeutic targets for colorectal cancer based on metabolic regulation.
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li et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75f37c6e9836116a2a6be
https://doi.org/https://doi.org/10.1016/j.bbalip.2026.159730