Dropped head syndrome following dose escalation of donepezil

Key Points

• Dropped head syndrome developed after increasing the donepezil dosage, affecting neck muscle tone.
• Patient demonstrated significant decline in cognitive function alongside physical symptoms within weeks post-escalation.
• Observational analysis of dosage effects, detailing the timeline of neurological changes and physical presentations.
• This case highlights the need for monitoring neuromuscular symptoms following treatments like donepezil; further investigation is warranted.