Association of plasma matrix metalloproteinase-9 and osteopontin levels with Apolipoprotein E genotypes of patients with mild cognitive impairment and Alzheimer’s disease

Key Points

• Increased plasma matrix metalloproteinase-9 levels correlate with Alzheimer's disease severity and cognitive decline.
• Statistical analysis revealed significant differences in osteopontin levels among different Apolipoprotein E genotypes.
• Assessment involved a comparative observational analysis of patients diagnosed with mild cognitive impairment and Alzheimer's disease.
• Findings highlight potential biomarkers for disease progression and genetic risk factors in neurodegenerative disorders.