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Carbonic anhydrase inhibitors against cerebrovascular dysfunction in Alzheimer's disease and dementias | Synapse
March 3, 2026
Carbonic anhydrase inhibitors against cerebrovascular dysfunction in Alzheimer's disease and dementias
NL
Nicole Lemon
EC
Elisa Canepa
NL
Nicole L Lemon
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Key Points
Cerebrovascular dysfunction improves with carbonic anhydrase inhibitors, indicating their potential in treating Alzheimer's disease.
Evidence comes from biomarkers reflecting neurodegeneration in dementia patients showing notable changes after intervention.
Analysis of cerebrovascular responses to carbonic anhydrase inhibitors reveals their significant role in managing Alzheimer's-related dysfunction.
These findings support further investigation into cerebrovascular targeting for therapies in neurodegenerative conditions like Alzheimer's.
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Lemon et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75f81c6e9836116a2aed6
https://doi.org/https://doi.org/10.1016/j.jns.2025.125168
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