Hyperintense basal ganglia on T1-MRI in two patients with elevated serum manganese due to cirrhosis

Key Points

• Hyperintense basal ganglia were observed on T1-MRI scans, indicating a potential link to manganese.
• Two patients exhibited elevated serum manganese levels, contributing to MRI findings of brain changes.
• MRI analysis showed that abnormal manganese levels correlated with changes in the basal ganglia.
• Findings highlight the need for further investigation into manganese's role in brain pathology during cirrhosis.