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The Risk of BK-Virus Hemorrhagic Cystitis in the Era of Post-Transplantation Cyclophosphamide | Synapse
March 3, 2026
The Risk of BK-Virus Hemorrhagic Cystitis in the Era of Post-Transplantation Cyclophosphamide
MM
Marco Mielcarek
University of Washington
HX
Hu Xie
Fred Hutch Cancer Center
WL
Wendy M. Leisenring
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Key Points
Hemorrhagic cystitis risk is elevated following transplantation with cyclophosphamide use, indicating a need for close monitoring.
Increased incidence of BK-virus-related complications was noted in patients receiving cyclophosphamide treatment post-transplant.
This analysis included a comprehensive review of transplant patient records focusing on viral infections and immunosuppression effects.
These findings emphasize the need for revised guidelines to address complications post-transplant therapy.
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Cite This Study
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Mielcarek et al. (Sun,) studied this question.
synapsesocial.com/papers/69a75ff9c6e9836116a2c5cf
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.797