Dual anticancer and antimicrobial activity of thiolated alginate–poly(β-amino ester) nanoparticles for oral delivery

Key Points

• Nanoparticles exhibit both anticancer and antimicrobial activity, enhancing therapeutic options.
• Significant reduction of bacterial growth observed at concentrations above 50 µg/mL in vitro.
• Analysis using thiolated alginate and poly(β-amino ester) nanoparticles shows effective drug delivery.
• The findings suggest that these nanoparticles may represent a novel approach for combined therapies.