What does this research mean for the field?

The SCORE-2 cardiovascular risk score classifies a higher proportion of Colombian adults at risk of type 2 diabetes as high risk compared to the more conservative ASCVD and HEARTS scales, resulting in low agreement between the tools and highlighting the need for local validation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

March 3, 2026Open Access

Comparative evaluation of ASCVD, SCORE-2, and HEARTS risk scores in Colombian adults at risk of type 2 diabetes: stratification, concordance, and associated factors

Key Points

Higher cardiovascular risk classification was seen with the SCORE-2 scale, while ASCVD and HEARTS were more conservative.
A significant disagreement between the risk assessment scales underscores the importance of localized validation for accuracy.

Structured PICO

How do ASCVD, SCORE-2, and HEARTS risk scores compare in stratifying cardiovascular risk and what is their concordance in Colombian adults at risk of type 2 diabetes?

Population

Colombian adults at risk of type 2 diabetes

Intervention

Cardiovascular risk assessment using SCORE-2, ASCVD, and HEARTS risk scores

Outcome

Risk stratification and concordance between scales

There is low concordance between ASCVD, SCORE-2, and HEARTS risk scores in Colombian adults at risk for type 2 diabetes, highlighting the need for local validation of cardiovascular risk assessment tools.

Abstract

SCORE-2 classified a higher proportion of individuals as high cardiovascular risk, while ASCVD and HEARTS were more conservative. The low level of agreement between the scales highlights the need for local validation of CVR assessment tools.

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