WATER III: A Prospective, Partially Randomized Trial of Aquablation Therapy Versus Transurethral Laser Enucleation of the Prostate for Treatment of Lower Urinary Tract Symptoms

Key Points

• Aquablation therapy achieved noninferior relief of lower urinary tract symptoms in comparison to transurethral laser enucleation—this indicates effectiveness.
• Short-term follow-up reveals that aquablation maintained ejaculation preservation and reduced the incidence of stress urinary incontinence, promoting good outcomes.
• This prospective trial included a partially randomized design, assessing safety and symptom relief across both interventions.
• The findings highlight the benefits of aquablation therapy, suggesting a viable option with specific advantages over traditional methods.