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Correction: Reduced Fc-mediated antibody responses after COVID-19 mRNA vaccination in a cohort of people living with HIV-1 | Synapse
March 3, 2026
Open Access
Correction: Reduced Fc-mediated antibody responses after COVID-19 mRNA vaccination in a cohort of people living with HIV-1
JK
Jéromine Klingler
PR
Priyanka Gadam Rao
Icahn School of Medicine at Mount Sinai
JB
Juan C. Bandrés
James J. Peters VA Medical Center
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Key Points
Antibody responses were significantly reduced after mRNA vaccination, indicating potential immune challenges for people living with HIV-1.
Participants living with HIV-1 exhibited lower Fc-mediated responses compared to non-infected individuals, with differences noted in immunogenicity.
Assessment of immune response metrics revealed limitations in vaccine efficacy among HIV-1 cohorts, emphasizing the need for tailored interventions.
This finding highlights the requirement for further investigation into mRNA vaccine adaptations to improve immunity for immunocompromised groups.
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Klingler et al. (Tue,) studied this question.
synapsesocial.com/papers/69a7604cc6e9836116a2ce7c
https://doi.org/https://doi.org/10.1038/s41598-025-33524-3
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