Incidence, Timing, and Clinical Correlates of Streptococcus Mitis Bloodstream Infection in Allogeneic Hematopoietic Cell Transplant Recipients Receiving Ciprofloxacin Prophylaxis: A Single-Center Retrospective Study

Key Points

• Bloodstream infections increased among hematopoietic cell transplant recipients receiving ciprofloxacin during their treatment.
• Out of the cases, 20% occurred within the first month post-transplant, highlighting critical timing for infection risk.
• Study employs a retrospective design, analyzing patient records from a single center to assess infection incidence and timing.
• Findings indicate that prophylactic strategies may need adjustments to address the observed infection risk.