Induction of Immune Tolerance after Haploidentical Stem Cell Transplantation Following Solid Organ Transplantation in Patients with Sickle Cell Disease
Key Points
Immune tolerance is successfully induced in patients with sickle cell disease undergoing haploidentical stem cell transplantation.
Key metric shows a reduced incidence of graft-versus-host disease after transplantation in these patients.
This observational analysis focuses on patients who received solid organ transplantation prior to stem cell therapy.
Success in inducing tolerance may improve overall outcomes; further studies are needed to validate these findings.
Indução de Tolerância Imune após Transplante de Células-Tronco Haplóides Seguida de Transplante de Órgãos Sólidos em Pacientes com Doença Falciforme | Synapse