Quercetin-Loaded Avocado Oil Nanoemulsion Reverses High-fat and High-carbohydrate Diet-Induced Testicular Dysfunction: Role of Oxidative Stress and NPY Signaling in a Randomized Trial

Key Points

• Testicular dysfunction is improved with avocado oil nanoemulsion treatment, reversing diet-induced effects.
• The combined NAOQu formulation showed enhanced protective effects compared to quercetin or avocado oil alone.
• Assessment using randomized trial methodology confirms the efficacy of the nanoemulsion formulation in addressing oxidative stress.
• These findings highlight the potential of avocado oil nanoemulsions for future male reproductive health interventions.