Reduced IL-2 Intensity Is Associated with Improved Outcomes in Tumor-Infiltrating Lymphocyte Therapy: A Meta-Analysis

Key Points

• Improved outcomes are associated with lower IL-2 intensity, enhancing the effectiveness of tumor-infiltrating lymphocyte therapy.
• The meta-analysis included comprehensive evaluations of multiple studies providing a robust assessment of IL-2 effects.
• Findings indicate that immune therapy can be optimized by adjusting cytokine intensity for better patient results.
• These insights call for further investigations to refine treatment strategies in cancer immunotherapy.