Background: Cardiopulmonary bypass (CPB) is an essential component of cardiac surgery and gas flow is recognised as a critical element of the CPB process. Objectives: In this retrospective study, we aimed to compare these two different initial gas flow methods (fixed initial gas flow rate and personalised gas flow rate) used in the management of the sweep gas flow rate during CPB. Methods: In this retrospective study, those whose baseline gas flow rate was determined according to patient blood gas values measured after induction of anaesthesia were defined as Group 1 (patient-based personalised gas flow rate) and those whose baseline gas flow rate was calculated by the formula BSA x 1.509 were defined as Group 2 (those with a fixed baseline gas flow rate). After applying the exclusion criteria, adult patients who underwent consecutive CPB-guided cardiac surgery were included in the study. The early clinical outcomes of the groups were then compared. Results: In this study, demographic and descriptive data of the groups were similar (p > 0.05). PCO2 , PO2 , pH, glucose intensive care unit stay time and hospital stay time values of the groups were similar and there was no difference between the two groups in terms of these parameters (p > 0.05). However, lactate, base deficit and intubation times of the groups were significantly different and were higher in Group 2 (p = 0.035; p = 0.009; p = 0.005, respectively). Conclusion: The findings that an individualised gas flow rate provides better clinical outcomes than a fixed gas flow rate may lead to the adoption of a new approach to patient management during CPB. Consequently, a patient-based individualised gas flow rate rather than a fixed rate (BSA x 1.509) in gas flow management during CPB may lead to better clinical outcomes
Amaç et al. (Wed,) studied this question.