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Long-Term Effects of Gender-Affirming Hormone Therapy from Adolescence to Adulthood on Voice | Synapse
March 3, 2026
Open Access
Long-Term Effects of Gender-Affirming Hormone Therapy from Adolescence to Adulthood on Voice
SC
Silvia Ciancia
Ghent University Hospital
CL
Clara Leyns
DK
Daniel Klink
Ghent University Hospital
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Key Points
Voice changes persist over time following gender-affirming hormone therapy, influencing identity and social interaction.
The analysis reveals notable physiological changes in participants' voices due to therapy across various age groups.
This study employs a longitudinal approach to assess voice outcomes related to hormone therapy from adolescence through adulthood.
These findings highlight the importance of understanding long-term effects in shaping healthcare guidelines and support for transgender individuals.
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Ciancia et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76104c6e9836116a2e822
https://doi.org/https://doi.org/10.1016/j.jvoice.2026.01.048