The pore-forming toxin Candidalysin dampens the autophagy-related plasma membrane stress response during Candida albicans invasion of epithelial cells.

Key Points

• Candidalysin reduces the autophagy-related stress response during Candida albicans invasion.
• Key evidence shows that candidalysin significantly dampens membrane stress response.
• Observational analysis reveals the interaction between candidalysin and epithelial cells during invasion.
• This study highlights the important role of autophagy in defending against fungal invasion, needing further exploration.

Abstract