Density-dependent dose response to field width and pitch variations in helical tomotherapy: a multi-density phantom and piecewise regression analysis

Key Points

• Dose response varies with changing field width and pitch in helical tomotherapy, indicating a complex interaction with density.
• The piecewise regression analysis shows significant density-dependent differences in dose delivery patterns.
• Assessment using a multi-density phantom reveals how treatment effectiveness can change based on varying physical conditions.
• Further evaluation of clinical outcomes is warranted to enhance personalized treatment strategies in radiation therapy.