Bupleurum chinense ameliorates metabolic-associated fatty liver disease by modulating Sirtuin 6

Key Points

• Bupleurum chinense enhances lipid metabolism, addressing metabolic-associated fatty liver disease effectively.
• Observational analysis indicated that Sirtuin 6 modulation significantly reduced liver fat accumulation.
• The study identifies antioxidant activity as a key mechanism underlying the therapeutic effects of Bupleurum chinense.
• This work highlights the potential of plant-derived compounds in managing metabolic disorders.