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Dual targeted therapy with biologic agents and small molecules in refractory inflammatory arthritis: clinical outcomes and safety profile | Synapse
March 3, 2026
Dual targeted therapy with biologic agents and small molecules in refractory inflammatory arthritis: clinical outcomes and safety profile
VC
Valeria Caggiano
University of Siena
AV
Antonio Vitale
University of Siena
JS
Jessica Sbalchiero
University of Siena
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Key Points
Improved clinical outcomes were observed in patients receiving dual targeted therapy for inflammatory arthritis.
The safety profile indicated low adverse events, with only 10% experiencing significant side effects from treatment.
Observational analysis assessed patient responses to both biologic agents and small molecules over a 6-month period.
Results highlight the need for more comprehensive trials to validate dual therapy's effectiveness and safety in broader populations.
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Caggiano et al. (Thu,) studied this question.
synapsesocial.com/papers/69a766e0badf0bb9e87dec38
https://doi.org/https://doi.org/10.1007/s11739-026-04274-5