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circVEGFC strengthens high glucose-induced trophoblast cell inflammation and apoptosis | Synapse
March 3, 2026
circVEGFC strengthens high glucose-induced trophoblast cell inflammation and apoptosis
MF
Miao Fang
Northeastern University
CW
Chunli Wang
Key Points
Inflammation and apoptosis are significantly increased in trophoblast cells exposed to high glucose levels.
The key evidence shows a notable rise in circvegfc expression coinciding with these cellular responses.
This analysis utilized trophoblast cell cultures to investigate the effects of high glucose on cellular mechanisms.
These findings highlight the potential link between high glucose and trophoblast dysfunction, affecting pregnancy outcomes.
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Fang et al. (Fri,) studied this question.
synapsesocial.com/papers/69a76702badf0bb9e87df477
https://doi.org/https://doi.org/10.1016/j.jri.2026.104851