Thymidine induces macrophage M1 polarization in radiation-induced-lung-injury by ATF3/p38 pathway

Key Points

• Thymidine induces macrophage M1 polarization, enhancing inflammatory responses in lung injury.
• The activation of ATF3 and p38 pathway plays a crucial role in this immune response.
• This analysis highlights the molecular mechanisms underlying radiation-induced lung injury and potential interventions.
• Significant focus on the ATF3/p38 pathway could enable new strategies for managing lung injury from radiation.