Xylosyltransferase-I in knee arthrofibrosis: Mechanistic insights and translational implications

Key Points

• Xylosyltransferase-I shows potential as a novel synovial biomarker for arthrofibrosis, enabling better diagnostics.
• Targeting xylosyltransferase-I alongside inhibitors of core pathways may enhance therapeutic approaches in TKA.
• The analysis focuses on the mechanistic role of xylosyltransferase-I in regulating fibrosis response.
• Further exploration of xylosyltransferase-I could lead to improved outcomes in managing knee arthrofibrosis.