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How do genetic polymorphisms influence the efficacy of age-related macular degeneration treatments? A systematic review and meta-analysis | Synapse
March 3, 2026
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How do genetic polymorphisms influence the efficacy of age-related macular degeneration treatments? A systematic review and meta-analysis
KC
Kai-Yang Chen
Chang Gung Memorial Hospital
HC
Hoi-Chun Chan
China Medical University
CC
Chi-Ming Chan
Fu Jen Catholic University
Key Points
Efficacy of treatments varies significantly due to genetic polymorphisms.
Strong correlations were found between specific polymorphisms and treatment outcomes.
Systematic review and meta-analysis of various studies provided comprehensive insights.
Understanding these genetic factors may enhance personalized treatment approaches.
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Chen et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76791badf0bb9e87e174b
https://doi.org/https://doi.org/10.1007/s00417-025-07058-3