Unexplained Elevated Cell-Free DNA in a Kidney Transplant Patient With Stable Clinical Parameters: A Case Report and Literature Review

Key Points

• Elevated cell-free DNA levels indicate potential underlying issues in kidney transplant function, despite stability.
• Measured cell-free DNA indicated levels above normal ranges, prompting further investigation into graft status.
• Observational analysis discovered unexpected biomarkers in a kidney transplant patient with no overt clinical changes.
• Highlights the need for continued monitoring of graft health, even when standard clinical parameters remain stable.