Correction Paschou et al., Dysregulated proteostasis in p.A53T-α-Synuclein astrocytes aggravates Lewy-like neuropathology in a Parkinson’s disease iPSC model
Key Points
Neuropathology worsens significantly due to dysregulated proteostasis in astrocytes.
Findings highlight a connection between p.A53T-α-synuclein and increased Lewy-like features.
Analysis uses an induced pluripotent stem cell model specifically for Parkinson’s disease.
Highlights the need for targeted interventions in astrocyte function in Parkinson’s disease.
Correction Paschou et al., Dysregulated proteostasis in p.A53T-α-Synuclein astrocytes aggravates Lewy-like neuropathology in a Parkinson’s disease iPSC model | Synapse