Effects of asprosin on high-fat diet–induced liver injury in rats: a histopathological, immunohistochemical, and molecular study

Key Points

• The research investigates asprosin's role in preventing liver injury caused by a high-fat diet in rats.
• Conducted histopathological and immunohistochemical analyses on liver tissue samples.
• Assessed oxidative stress and apoptosis markers in relation to asprosin treatment.
• Utilized molecular techniques to evaluate the underlying protective mechanisms.
• Asprosin significantly reduced oxidative stress markers in liver tissue.
• Observed decrease in apoptosis in liver cells in asprosin-treated groups.
• Histopathological examination showed improvement in liver morphology in treated rats.