What question did this study set out to answer?

March 10, 2026

Medication use during pregnancy in Japan from 2005 to 2019: Trends and safety considerations

MAMotohiko AdomiBrigham and Women's Hospital TSTakamasa SakaiUniversity of Oslo TITomofumi IshikawaTohoku University

Key Points

To investigate trends in medication use during pregnancy in Japan from 2005 to 2019 and assess safety concerns.
Analyzed data on medication prescriptions during pregnancy in Japan from 2005 to 2019.
Categorized medications into classes based on their teratogenic risks.
Identified trends in the utilization of these medications over the specified period.
A significant increase in the utilization of several medication classes was noted.
Many commonly dispensed medications lack adequate safety evidence for teratogenic effects in pregnant individuals.
The findings highlight the need for targeted safety evaluations of medications used by pregnant individuals in Japan.

Abstract

A significant proportion of medications commonly dispensed during pregnancy in Japan have inadequate teratogenic safety evidence. Several medication classes showed increasing utilization trends over the study period, emphasizing the urgent need for targeted safety evaluations in the Japanese population.

Perguntar à IA

Bookmark

View Full Paper

Cite This Study

Adomi et al. (Sat,) studied this question.

synapsesocial.com/papers/69af954870916d39fea4cab2 https://doi.org/https://doi.org/10.1002/ijgo.70860

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Perguntar à IA

Bookmark

View Full Paper