Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Key Points

• The research aims to explore how blood transcriptomic changes in horses indicate immune and physiological adaptations to training and racing.
• Conducted transcriptomic analysis on blood samples from horses before and after training and races.
• Identified stages of immune activation and adaptation using specified transcriptomic dynamics.
• Analyzed changes related to stress response post-race.
• Found distinct transcriptomic signatures that correspond with early immune activation, adaptation, and stress response.
• Identified potential molecular biomarkers that can help monitor training adaptation in horses.
• Revealed that horses experience systematic physiological changes linked to their training and competitive performance.