The Novel HLA‐DPB1*1759:01 Allele Was Identified by Next‐Generation Sequencing

Key Points

• The aim is to identify the novel HLA-DPB1*1759:01 allele through genetic sequencing techniques.
• Utilized next-generation sequencing technology for allele identification
• Focused on the genetic sequence of HLA-DPB1
• Compared variations at specific codon locations
• Identified HLA-DPB1*1759:01 as differing from HLA-DPB1*02:01:02:01
• Noted a change in exon 4 codon 221 from AGC to ATT