What question did this study set out to answer?

The aim is to explore the relationship between quantitative EEG changes and postoperative delirium (POD) and identify potential markers of vulnerability.

March 13, 2026Open Access

Quantitative EEG changes preceding and following postoperative delirium: a prospective, multicenter, cohort study

Key Points

The aim is to explore the relationship between quantitative EEG changes and postoperative delirium (POD) and identify potential markers of vulnerability.
Prospective multicenter cohort study design
Evaluation of preoperative and postoperative quantitative EEG measures
Assessment of beta amplitude-based connectivity in brain networks
Longitudinal monitoring of EEG changes after surgery
Identified reduced preoperative beta amplitude connectivity as a potential marker for neurophysiological vulnerability to POD
No significant longitudinal changes in EEG measures were observed three months post-surgery
Resting-state EEG networks may recover or compensate functionally in this cohort.

Abstract

This study identified reduced preoperative beta amplitude-based connectivity as a possible marker of neurophysiological vulnerability for POD. However, the absence of significant longitudinal changes in quantitative EEG measures suggests that resting-state EEG networks may functionally recover or compensate in this cohort at three months postoperative.

Quantitative EEG changes preceding and following postoperative delirium: a prospective, multicenter, cohort study

Key Points

Abstract

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