Crystallographic and EPR-based characterisation of Cu 2+ -binding to serum albumin: ATCUN coordination and additional sites

Key Points

• The aim is to characterise the binding affinity of Cu²⁺ to serum albumin and identify coordination sites.
• Employing crystallographic and EPR techniques
• Examining Cu²⁺ interactions with serum albumin
• Identifying ATCUN coordination and additional binding sites.
• Reveals specific binding affinity of Cu²⁺ to serum albumin
• Identifies key physiological roles in copper transport
• Finds additional coordination sites beyond ATCUN.