What does this research mean for the field?

Intensive cycling training increases serum calprotectin and PTX3 concentrations in professional cyclists. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to assess the impact of intensive cycling training on serum biomarkers in professional cyclists.

March 14, 2026

Intensive cycling training increases serum calprotectin and PTX3 concentrations in professional athletes

Key Points

This research aims to assess the impact of intensive cycling training on serum biomarkers in professional cyclists.
Measured serum concentrations of calprotectin and PTX3 in professional cyclists before and after intensive training.
Evaluated the correlation with other inflammation and metabolic biomarkers.
Serum calprotectin levels significantly increased after intensive cycling training.
PTX3 concentration also showed a significant increase post-training.
No changes were observed in other inflammation and metabolic biomarkers.

Abstract

Intensive cycling training leads to significant increase in both serum calprotectin and PTX3 concentration in professional cyclists. This increase is not associated with changes in other inflammation and metabolic biomarkers. Calprotectin and pentraxin 3 could serve as a sensitive, early and sports-related biomarkers of physiological stress.

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Cite This Study

Alfirević et al. (Sun,) studied this question.

synapsesocial.com/papers/69b4fc0eb39f7826a300cb02 https://doi.org/https://doi.org/10.23736/s0022-4707.26.17612-9

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