What question did this study set out to answer?

To investigate the renal adverse events associated with ibuprofen treatment following hip and knee arthroplasties.

March 15, 2026Open Access

Renal Adverse Events Associated With Ibuprofen Treatment After Hip and Knee Arthroplasties— A Protocol for the Preplanned Substudy of the PERISAFE Trial

Key Points

To investigate the renal adverse events associated with ibuprofen treatment following hip and knee arthroplasties.
Preplanned substudy within the PERISAFE trial framework
Ethical approvals from relevant Danish agencies
Focus on renal adverse effects post-surgery.
Identifying potential renal complications after ibuprofen use in surgical patients.

Abstract

The ethical approval for this substudy is included in the main PERISAFE trial, which has been approved by the Danish Medicine Agency, the National Committee on Health Research Ethics (EU CT no. 2022-502502-32-00), and the Danish Data Protection Agency (REG-149-2022).

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Authors

Christina Cleveland Westerdahl Laursen

Zealand University Hospital Køge

Klara Nørrekær Lund

Zealand University Hospital Køge

Troels Haxholdt Lunn

University of Copenhagen

Journals

Acta Anaesthesiologica Scandinavica

Actions

Institutions

University of Copenhagen

University of Southern Denmark

Copenhagen University Hospital

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Renal Adverse Events Associated With Ibuprofen Treatment After Hip and Knee Arthroplasties— A Protocol for the Preplanned Substudy of the PERISAFE Trial

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study