What does this research mean for the field?

Cardiac sarcoidosis is more frequent in males, with a male-to-female ratio of 70.3% to 29.7% among patients diagnosed with sarcoidosis. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

What question did this study set out to answer?

The aim is to evaluate the frequency of cardiac sarcoidosis among patients diagnosed with sarcoidosis.

March 17, 2026

Cardiac sarcoidosis is more frequent in males - Large cohort (n=1375) sarcoid patients analysis - 5 years experience in the National TB & Lung Diseases Research Institute in Warsaw, Poland

Key Points

The aim is to evaluate the frequency of cardiac sarcoidosis among patients diagnosed with sarcoidosis.
Retrospective analysis of patients with a diagnosis of sarcoidosis from 2008 to 2012.
Selection of patients with diagnosed cardiac involvement based on specific guidelines.
Data included demographic information and imaging results.
Among 1375 sarcoidosis patients, 64 exhibited cardiac involvement (4.7%).
The female-to-male ratio in cardiac cases was 19 to 45 (29.7% to 70.3%).
Males showed 2.34 times greater likelihood of cardiac involvement compared to females, with significant p-value (0.0023).

Abstract

Sarcoidosis is predominantly demonstrated in the respiratory tract, however granulomas can involve all other organs, including heart, what may be potentially life-threatening. The aim of study was to evaluate the incidence of cardiac sarcoidosis in the group of patients diagnosed or followed up due to sarcoidosis in two departments of the National TB 95% CI: 1.3559 to 4.0496, p = 0.0023. The median of time from the diagnosis of sarcoidosis to detection of heart involvement was 18.8 months (CI 90% range 0 to 8.9 years). Conclusion: Cardiac sarcoidosis was diagnosed in the similar percentage as in previously published data, but was significantly more frequently in males.

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Cardiac sarcoidosis is more frequent in males - Large cohort (n=1375) sarcoid patients analysis - 5 years experience in the National TB & Lung Diseases Research Institute in Warsaw, Poland

Key Points

Abstract

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