What question did this study set out to answer?

The aim is to develop and validate an automated staging calculator for pediatric cancers using Toronto guidelines.

March 18, 2026

Development and Validation of an Automated Pediatric Cancer Staging Calculator Using the Toronto Pediatric Cancer Stage Guidelines

Key Points

The aim is to develop and validate an automated staging calculator for pediatric cancers using Toronto guidelines.
Developed an automated staging tool based on Toronto Pediatric Cancer Stage Guidelines.
Validated the tool against expert human judgment for consistency and accuracy.
Implemented a workflow that flags uncertain cases for human review.
Achieved approximately 97% accuracy in staging pediatric cancers compared to human experts.
Demonstrated excellent consistency across independent runs of the tool.
Approximately 30% of cases required human adjudication due to uncertainty.

Abstract

We demonstrate the first automated staging system for pediatric cancers using standardized Toronto criteria. The tool showed high accuracy comparable to human experts and excellent consistency between independent runs. We propose a hybrid workflow that flags uncertain cases for human review, yielding approximately 97% accuracy with approximately 30% human adjudication.

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Discussion

Authors

Iyad Sultan

Anwar Al‐Nassan

Laith Alomari

Journals

Pediatric Blood & Cancer

Actions

Institutions

University of Jordan

Pennsylvania Hospital

King Hussein Cancer Center

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Development and Validation of an Automated Pediatric Cancer Staging Calculator Using the Toronto Pediatric Cancer Stage Guidelines

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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