Association between second-trimester sFlt-1/PlGF ratio and composite adverse neonatal outcome in patients with preeclampsia

Key Points

• This research aims to assess the predictive value of the second-trimester sFlt-1/PlGF ratio for adverse neonatal outcomes in patients with preeclampsia.
• Observational study design
• Assessment of sFlt-1 and PlGF levels in second trimester
• Evaluation of neonatal outcomes in preeclampsia cases
• sFlt-1/PlGF ratio is an independent predictor of composite adverse neonatal outcomes
• High-risk neonates can be identified early using this biomarker
• The predictive model informs personalized perinatal management strategies.