ABSTRACT Bisphenol A (BPA), an endocrine‐disrupting contaminant released from polymeric materials, requires ultrasensitive monitoring to safeguard water quality and public health. Here, we present a simple and low‐cost electrochemical sensor based on cetrimonium bromide (CTAB) and β‐cyclodextrin‐functionalized multi‐walled carbon nanotubes (MWCNT –β‐CD) integrated onto a screen‐printed carbon electrode (SPCE). BPA undergoes an adsorption‐controlled, two‐electron/two‐proton oxidation process at the CTAB/MWCNT–β‐CD/SPCE interface. Linear sweep voltammetry enabled a detection limit of 7.82 pM and a broad dynamic range of 10 pM–10 µ m . The picomolar sensitivity arises from synergistic CTAB‐mediated analyte preconcentration and the high surface area and conductivity provided by MWCNT–β‐CD. The sensor exhibited excellent stability, reproducibility, and selectivity in the presence of common inorganic, phenolic compounds, BPA analogues, and electroactive bimolecular species. Quantification in spiked bottled, tap, and lake water samples yielded recoveries of 90.36%–104.33%, consistent with LC–MS validation. These results demonstrate that CTAB/MWCNT–β‐CD‐modified SPCEs provide a robust and practical platform for on‐site ultratrace detection of BPA in environmental waters.
Ali et al. (Sun,) studied this question.