June 11, 2022Open Access

Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice

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Abstract

rTMS could alleviate cerebral I/R injury induced locomotor deficits and neuronal pyroptosis by modulating the microglial polarization. It is expected that these data will provide novel insights into the mechanisms of rTMS protecting against cerebral I/R injury and potential targets underlying neuronal pyroptosis in the early phase of stroke.

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Luo et al. (Sat,) studied this question.

synapsesocial.com/papers/69cd0448e0d6becfeecf4345 https://doi.org/https://doi.org/10.1186/s12974-022-02501-2

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