What are the primary hemodynamic correlates of higher pulse pressure across the adult age spectrum?
Age-related increases in pulse pressure are primarily driven by a larger forward pressure wave rather than wave reflection.
Higher pulse pressure at any age and higher pulse pressure with advancing age is associated predominantly with a larger forward pressure wave. The influence of wave reflection on age-related differences in pulse pressure was minor.
Mitchell et al. (Tue,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: