April 23, 2025Open Access

Hemolysis after pulsed-field ablation in pulmonary vein isolation for atrial fibrillation: A prospective controlled trial

Structured PICO

Does pulsed-field ablation cause hemolysis-induced AKI in patients undergoing pulmonary vein isolation for atrial fibrillation?

Population

Patients undergoing pulmonary vein isolation for atrial fibrillation

Intervention

Pulsed-field ablation (PFA) using a multispline catheter with 8 and 16 applications per pulmonary vein and focal PFA using CardioFocus platform

Outcome

Hemolysis-induced acute kidney injury (AKI)safety

Pulsed-field ablation for pulmonary vein isolation appears safe regarding the risk of hemolysis-induced acute kidney injury.

Abstract

PFA using a multispline catheter with 8 and 16 applications per PV and focal PFA using CardioFocus (CardioFocus Inc., Massachusetts) platform showed no safety concerns with respect to hemolysis-induced AKI.

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Cite This Study

Heiden et al. (Wed,) studied this question.

synapsesocial.com/papers/69d570e175589c71d767dfc2 https://doi.org/https://doi.org/10.1016/j.hrthm.2025.04.038

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