June 21, 2023Open Access

Association between neutrophil percentage-to-albumin ratio (NPAR), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and long-term mortality in community-dwelling adults with heart failure: evidence from US NHANES 2005–2016

Structured PICO

Are elevated NPAR, NLR, and PLR associated with long-term mortality in community-dwelling adults with heart failure?

Population

Community-dwelling adults with heart failure from US NHANES 2005–2016

Intervention

Elevated neutrophil percentage-to-albumin ratio (NPAR), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR)

Outcome

Long-term all-cause mortalityhard clinical

Elevated NPAR and NLR are associated with increased all-cause mortality in heart failure patients, but have low predictive value on their own.

Abstract

In conclusion, elevated NPAR and NLR but not PLR are independently associated with increased all-cause mortality among community-dwelling individuals with HF. However, the predictive performance of NPAR and NLR alone on mortality was low.

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