July 1, 1997

Kawaguchipeptin B, an Antibacterial Cyclic Undecapeptide from the Cyanobacterium Microcystis aeruginosa

KIKeishi IshidaLeibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)HMHisashi MatsudaKanazawa University MMMasahiro MurakamiUniversity of Potsdam

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Abstract

Kawaguchipeptin B, an antibacterial cyclic undecapeptide, was isolated from the cultured cyanobacterium Microcystis aeruginosa (NIES-88). Its structure was elucidated as 1 on the basis of 2D NMR data and chemical degradation. Kawaguchipeptin B (1) inhibited the growth of the Gram-positive bacterium Staphylococcus aureus at a concentration of 1 microgram/mL (MIC).

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Ishida et al. (Tue,) studied this question.

synapsesocial.com/papers/69d72957a98988943d563bc4 https://doi.org/https://doi.org/10.1021/np970146k

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