January 5, 2007Open Access

Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury

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Abstract

Leflunomide afforded protection against APAP-induced hepatotoxicity in mice through inhibition of JNK-mediated activation of mitochondrial permeabilization.

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Latchoumycandane et al. (Fri,) studied this question.

synapsesocial.com/papers/69d74192b1cb92dd1bb8a389 https://doi.org/https://doi.org/10.1002/hep.21475

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