Does cumulative exposure to hyperlipidemia in young adulthood increase the long-term risk of coronary heart disease?
Prolonged exposure to even moderate elevations in non-HDL cholesterol in young adulthood increases future CHD risk, suggesting a potential benefit for earlier aggressive primary prevention.
Cumulative exposure to hyperlipidemia in young adulthood increases the subsequent risk of CHD in a dose-dependent fashion. Adults with prolonged exposure to even moderate elevations in non-high-density lipoprotein cholesterol have elevated risk for future CHD and may benefit from more aggressive primary prevention.
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Circulation
Boston University
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Navar‐Boggan et al. (Tue,) studied this question.