In these cohorts of health professionals, weight gain during adulthood was associated with significantly increased risk of major chronic diseases and decreased odds of healthy aging. These findings may help counsel patients regarding the risks of weight gain.

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Zheng et al. (Tue,) studied this question.

synapsesocial.com/papers/69d8c3a48c03fbaff8bf0044 https://doi.org/https://doi.org/10.1001/jama.2017.7092

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1Successful Aging1997 · 3,697 citations
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Successful Aging1997 · 3,697 citations
2Body-mass index and mortality2009 · 25 citations
3Rates of weight change for black and white Americans over a twenty year period2003 · 211 citations
4The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study2014 · 3,558 citations
5Invited Commentary: Body Mass Index and Mortality2013 · 5 citations